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Salidroside targets the Notch1/Hes5 axis to reconstruct the molecular innate immune–vascular network and correlates with repair after ischemic stroke

BackgroundIschemic stroke (IS) induces profound dysregulation of the neuro–molecular innate immune–vascular network, yet the molecular immune states and regulatory mechanisms of key cellular subpopulations remain insufficiently defined. Although traditional Chinese medicine (TCM) exhibits multi-targ...

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Autori principali: Jing Zeng, Xiaohua Huang, Jingyi Zeng, Qi Huang, Wenyi Song, Youfeng Xie, Guining Liang, Qingyan Wei, Yating Lan, Donghua Zou, Rongjie Li, Lian Gu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-02-01
Serie:Frontiers in Immunology
Soggetti:
Hes5
ischemic stroke
molecular innate immunity
Notch1
salidroside
traditional Chinese medicine
Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1756559/full
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