Salidroside targets the Notch1/Hes5 axis to reconstruct the molecular innate immune–vascular network and correlates with repair after ischemic stroke

BackgroundIschemic stroke (IS) induces profound dysregulation of the neuro–molecular innate immune–vascular network, yet the molecular immune states and regulatory mechanisms of key cellular subpopulations remain insufficiently defined. Although traditional Chinese medicine (TCM) exhibits multi-targ...

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Detalhes bibliográficos

Principais autores:	Jing Zeng, Xiaohua Huang, Jingyi Zeng, Qi Huang, Wenyi Song, Youfeng Xie, Guining Liang, Qingyan Wei, Yating Lan, Donghua Zou, Rongjie Li, Lian Gu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
coleção:	Frontiers in Immunology
Assuntos:	Hes5 ischemic stroke molecular innate immunity Notch1 salidroside traditional Chinese medicine
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1756559/full
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