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DOT-1.1-dependent H3K79 methylation promotes normal meiotic progression and meiotic checkpoint function in C. elegans.

Epigenetic modifiers are emerging as important regulators of the genome. However, how they regulate specific processes during meiosis is not well understood. Methylation of H3K79 by the histone methyltransferase Dot1 has been shown to be involved in the maintenance of genomic stability in various or...

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Detalles Bibliográficos
Principais autores: Laura I Lascarez-Lagunas, Esther Herruzo, Alla Grishok, Pedro A San-Segundo, Mónica P Colaiácovo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Genetics
Acceso en liña:https://doi.org/10.1371/journal.pgen.1009171
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