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DOT-1.1-dependent H3K79 methylation promotes normal meiotic progression and meiotic checkpoint function in C. elegans.

Epigenetic modifiers are emerging as important regulators of the genome. However, how they regulate specific processes during meiosis is not well understood. Methylation of H3K79 by the histone methyltransferase Dot1 has been shown to be involved in the maintenance of genomic stability in various or...

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Autori principali: Laura I Lascarez-Lagunas, Esther Herruzo, Alla Grishok, Pedro A San-Segundo, Mónica P Colaiácovo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2020-10-01
Serie:PLoS Genetics
Accesso online:https://doi.org/10.1371/journal.pgen.1009171
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