Phosphodiesterase 4 is overexpressed in keloid epidermal scars and its inhibition reduces keratinocyte fibrotic alterations
Abstract Background Epidermal remodeling and hypertrophy are hallmarks of skin fibrotic disorders, and keratinocyte to mesenchymal (EMT)-like transformations drive epidermis alteration in skin fibrosis such as keloids and hypertrophic scars (HTS). While phosphodiesterase 4 (PDE4) inhibitors have sho...
Zapisane w:
| Główni autorzy: | , , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2024-09-01
|
| Seria: | Molecular Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s10020-024-00906-8 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
