Thiazolo-pyridopyrimidines: An in silico evaluation as a lead for CDK4/6 inhibition, synthesis and cytotoxicity screening against breast cancer cell lines
Introduction: Pyridopyrimidines belong to a class of compounds characterized by the presence of nitrogen as heteroatoms. These compounds exhibit diverse biological effects, particularly showing promise as anticancer agents, including actions that inhibit CDK4/6. Methods: We designed and synthesized...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Tabriz University of Medical Sciences
2024-07-01
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| Серии: | BioImpacts |
| Предметы: | |
| Online-ссылка: | https://bi.tbzmed.ac.ir/PDF/bi-14-29951.pdf |
| Метки: |
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