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Inhibition of oxidative stress and NLRP3 inflammasome by Saikosaponin-d alleviates acute liver injury in carbon tetrachloride-induced hepatitis in mice

NLRP3 inflammasome activation results in severe liver inflammation and injury. Saikosaponin-d (SSd) possesses anti-inflammatory and hepatoprotective effects. This study aimed to determine the protective effects of SSd on carbon tetrachloride (CCl 4 )-induced acute liver injury in mice, and whether o...

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Bibliografske podrobnosti
Principais autores: Yirong Chen, Renye Que, Liubing Lin, Yanting Shen, Jinkai Liu, Yong Li
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publishing 2020-08-01
Serija:International Journal of Immunopathology and Pharmacology
Online dostop:https://doi.org/10.1177/2058738420950593
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