Estrogen receptor β activation alleviates inflammatory bowel disease by suppressing NLRP3-dependent IL-1β production in macrophages via downregulation of intracellular calcium level

Introduction: Although several estrogen receptor β (ERβ) agonists have been reported to alleviate IBD, the pivotal mechanism remains obscure. Objectives: To examine the effects and mechanisms of ERβ activation on cytokine/chemokine networks in colitis mice. Methods: Dextran sulfate sodium salt (DSS)...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Yanrong Zhu, Yilei Guo, Pengxiang Guo, Jing Zhang, Yue He, Yufeng Xia, Zhifeng Wei, Yue Dai
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-05-01
Edice:	Journal of Advanced Research
Témata:	Estrogen receptor β Inflammatory bowel disease Interleukin-1β Inflammasome Calcium-sensing receptor
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2090123224002285
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!