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Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies.

Parkinson's disease (PD) is one of the most common neurodegenerative diseases. It is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. Another feature is represented by the formation in these cells of inclusions called Lewy bodies (LB), principally...

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Príomhchruthaitheoirí: Gaia Codolo, Nicoletta Plotegher, Tommaso Pozzobon, Marco Brucale, Isabella Tessari, Luigi Bubacco, Marina de Bernard
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2013-01-01
Sraith:PLoS ONE
Rochtain ar líne:http://europepmc.org/articles/PMC3561263?pdf=render
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