Conformational equilibria in monomeric alpha-synuclein at the single-molecule level.
Human alpha-Synuclein (alphaSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A full comprehension of the structure and dynamics of early intermediates leading to the aggregated states is an unsolved problem of essential imp...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2008-01-01
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| Col·lecció: | PLoS Biology |
| Accés en línia: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18198943/?tool=EBI |
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