Prognostic significance and interplay of circulatory PCSK-9–ApoCIII–chemokine axis in type 2 diabetes and its complications: a pilot study in North Indian patients

Abstract Background Proprotein convertase subtilisin kexin/type-9 (PCSK-9) regulates cholesterol homeostasis through lysosomal degradation of LDL-R and also acts as a pleiotropic mediator of inflammation. Emerging evidence links PCSK-9 to diabetes pathogenesis. Given the genetic diversity and distin...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Mohd Waiz, Sahir Sultan Alvi, Parvej Ahmad, Bodor Bin Sheeha, Paridhi Puri, Irfan Ahmad, Saheem Ahmad, M. Salman Khan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SpringerOpen 2026-04-01
Colecção:	The Egyptian Journal of Internal Medicine
Assuntos:	Type-2 Diabetes PCSK-9 ApoCIII CXCL2 MCP-1 Nephropathy
Acesso em linha:	https://doi.org/10.1186/s43162-026-00624-z
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!