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Prognostic significance and interplay of circulatory PCSK-9–ApoCIII–chemokine axis in type 2 diabetes and its complications: a pilot study in North Indian patients

Abstract Background Proprotein convertase subtilisin kexin/type-9 (PCSK-9) regulates cholesterol homeostasis through lysosomal degradation of LDL-R and also acts as a pleiotropic mediator of inflammation. Emerging evidence links PCSK-9 to diabetes pathogenesis. Given the genetic diversity and distin...

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Principais autores: Mohd Waiz, Sahir Sultan Alvi, Parvej Ahmad, Bodor Bin Sheeha, Paridhi Puri, Irfan Ahmad, Saheem Ahmad, M. Salman Khan
Formato: Artigo
Idioma:Inglês
Publicado: SpringerOpen 2026-04-01
Series:The Egyptian Journal of Internal Medicine
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Acceso en liña:https://doi.org/10.1186/s43162-026-00624-z
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