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Inhibition of Midkine Augments Osteoporotic Fracture Healing.

The heparin-binding growth and differentiation factor midkine (Mdk) is proposed to negatively regulate osteoblast activity and bone formation in the adult skeleton. As Mdk-deficient mice were protected from ovariectomy (OVX)-induced bone loss, this factor may also play a role in the pathogenesis of...

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Autors principals: Melanie Haffner-Luntzer, Julia Kemmler, Verena Heidler, Katja Prystaz, Thorsten Schinke, Michael Amling, Anna Kovtun, Anna E Rapp, Anita Ignatius, Astrid Liedert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2016-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC4943649?pdf=render
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