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The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing.

Wnt signaling is a key regulator of bone metabolism and fracture healing. The canonical Wnt/β-catenin pathway is regarded as the dominant mechanism, and targeting this pathway has emerged as a promising strategy for the treatment of osteoporosis and poorly healing fractures. In contrast, little is k...

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Bibliografski detalji
Glavni autori: Aline Heilmann, Thorsten Schinke, Ronny Bindl, Tim Wehner, Anna Rapp, Melanie Haffner-Luntzer, Claudia Nemitz, Astrid Liedert, Michael Amling, Anita Ignatius
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2013-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3877253?pdf=render
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