PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency
Abstract Pluripotency is established in E4.5 preimplantation epiblast. Embryonic stem cells (ESCs) represent the immortalization of pluripotency, however, their gene expression signature only partially resembles that of developmental ground-state. Induced PRAMEL7 expression, a protein highly express...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Nature
2024-02-01
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| Schriftenreihe: | EMBO Reports |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1038/s44319-024-00083-z |
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