Differences in Strength and Timing of the mtDNA Bottleneck between Zebrafish Germline and Non-germline Cells

We studied the mtDNA bottleneck in zebrafish to elucidate size, timing, and variation in germline and non-germline cells. Mature zebrafish oocytes contain, on average, 19.0 × 106 mtDNA molecules with high variation between oocytes. During embryogenesis, the mtDNA copy number decreases to ∼170 mtDNA...

Descripció completa

Dades bibliogràfiques

Autors principals:	Auke B.C. Otten, Tom E.J. Theunissen, Josien G. Derhaag, Ellen H. Lambrichs, Iris B.W. Boesten, Marie Winandy, Aafke P.A. van Montfoort, Katsiaryna Tarbashevich, Erez Raz, Mike Gerards, Jo M. Vanoevelen, Bianca J.C. van den Bosch, Marc Muller, Hubert J.M. Smeets
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2016-07-01
Col·lecció:	Cell Reports
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S221112471630763X
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!