A Nanos3-containing protein complex can activate RNA translation in primordial germ cells in vivo

Abstract Maintaining the germline fate requires tight post-transcriptional control of RNA function. Here, we investigate how primordial germ cell (PGC) identity is maintained in zebrafish and reveal that the conserved RNA-binding proteins Nanos3 and Dead End1 form a complex that safeguards PGC ident...

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Principais autores:	Antra Gupta, Arzu Melsa Basaran, Moritz Ophaus, Shantanu Madiwale, Martin Stehling, Michal Reichman-Fried, Katsiaryna Tarbashevich, Erez Raz
Format:	Artigo
Jezik:	Inglês
Izdano:	Springer Nature 2026-04-01
Serija:	EMBO Reports
Online dostop:	https://doi.org/10.1038/s44319-026-00781-w
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