Generation of functional mesothelial cells from human iPSCs that restore peritoneal integrity in experimental peritoneal injury

Abstract Background Long-term peritoneal injury results in loss of mesothelial integrity and impaired ultrafiltration, limiting the durability of peritoneal dialysis. Because primary human peritoneal mesothelial cells (PMCs) are difficult to obtain and expand, regenerative strategies for restoring p...

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Ngā kaituhi matua:	Tadashi Kato, Mayu Yamashita, Masahiro Yasuda, Yutaro Ando, Ryusuke Nakatsuka, Yasumasa Shirouzu, Tatsuya Fujioka, Masayuki Tsukasaki, Fumiyuki Hattori, Yoshihiro Taniyama, Hiroaki Ogata, Akiko Sakashita, Hirokazu Honda, Hirofumi Hitomi
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2026-04-01
Rangatū:	Stem Cell Research & Therapy
Ngā marau:	Induced pluripotent stem cells Peritoneal mesothelial cells Permeability Wound healing Peritoneal dialysis
Urunga tuihono:	https://doi.org/10.1186/s13287-026-05037-x
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!