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Synovial transcriptome analysis reveals ShenTong ZhuYu Tang alleviates osteoarthritis by targeting MMP-9 and immune microenvironment

Abstract Background This study aimed to elucidate key molecular alterations in the osteoarthritis (OA) synovial microenvironment through transcriptomic analysis and to investigate the multi-target mechanisms of ShenTong ZhuYu Tang (STZYT) using network pharmacology and molecular docking. Methods We...

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Bibliografische Detailangaben
Hauptverfasser: Tihong Liang, Bo Zhou, Changwen Gu, Guoxuan Peng, Xu Ning, Mingzhi Huang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-01-01
Schriftenreihe:Journal of Orthopaedic Surgery and Research
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Online-Zugang:https://doi.org/10.1186/s13018-025-06617-y
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