Ultrasound Combined With Microbubbles Loading BDNF Retrovirus to Open Blood–Brain Barrier for Treatment of Alzheimer’s Disease

Background: Brain-derived nerve growth factor (BDNF) is a promising effective target for the treatment of Alzheimer’s disease (AD). BDNF, which has a high molecular weight, has difficulty in crossing the blood–brain barrier (BBB). The study aimed to prepare microbubbles loading brain-derived nerve g...

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Autori principali:	Feng Wang, Xi-Xi Wei, Lian-Sheng Chang, Lei Dong, Yong-Ling Wang, Na-Na Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2021-03-01
Serie:	Frontiers in Pharmacology
Soggetti:	cationic microbubbles Alzheimer’s disease retrovirus BDNF blood-brain barrier
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2021.615104/full
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