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Visualization of spatiotemporal energy dynamics of hippocampal neurons by mass spectrometry during a kainate-induced seizure.

We report the use of matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry combined with capillary electrophoresis (CE) mass spectrometry to visualize energy metabolism in the mouse hippocampus by imaging energy-related metabolites. We show the distribution patterns of ATP, A...

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Autori principali: Yuki Sugiura, Ryo Taguchi, Mitsutoshi Setou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3062556?pdf=render
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