A mass spectrometry imaging and lipidomic investigation reveals aberrant lipid metabolism in the orthotopic mouse glioma

Lipids perform multiple biological functions and reflect the physiology and pathology of cells, tissues, and organs. Here, we sought to understand lipid content in relation to tumor pathology by characterizing phospholipids and sphingolipids in the orthotopic mouse glioma using MALDI MS imaging (MSI...

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Detalhes bibliográficos

Principais autores:	Hay-Yan J. Wang, Chiung-Yin Huang, Kuo-Chen Wei, Kuo-Chen Hung
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-12-01
coleção:	Journal of Lipid Research
Assuntos:	tumor pathology phospholipids sphingolipids MALDI MS imaging unsupervised clustering analysis LC-MS/MS
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227522001377
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