Heart-Specific and Conditional Deletion of the <i>Immt</i> Gene Reveals Its Role in Regulating Mitochondrial Structure and Total Heart Metabolism

Mitochondria comprise ~1/3rd of the volume of an adult ventricular cardiomyocyte. The gene <i>Immt</i> encodes the Mic60/Mitofilin protein that is hypothesized to organize the mitochondrial contact site and cristae organization system (MICOS) complex that generates mitochondrial cristae junctions be...

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Detalhes bibliográficos

Principais autores:	Yasuhide Kuwabara, Caitlin Keezer, Suh-Chin J. Lin, Akanksha Rajput, Jeffery D. Molkentin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
Colecção:	Cells
Assuntos:	mitochondria cardiac hypertrophy cardiomyocyte metabolism mitophagy
Acesso em linha:	https://www.mdpi.com/2073-4409/15/6/505
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