Canonical and Non-Canonical Roles of PFKFB3 in Brain Tumors

PFKFB3 is a bifunctional enzyme that modulates and maintains the intracellular concentrations of fructose-2,6-bisphosphate (F2,6-P2), essentially controlling the rate of glycolysis. PFKFB3 is a known activator of glycolytic rewiring in neoplastic cells, including central nervous system (CNS) neoplas...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Reinier Alvarez, Debjani Mandal, Prashant Chittiboina
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-10-01
Цуврал:	Cells
Нөхцлүүд:	PFKFB3 PFK-2 tumorigenic reprogramming metabolic reprogramming hypoxia glycolysis
Онлайн хандалт:	https://www.mdpi.com/2073-4409/10/11/2913
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!