Micheliolide attenuates sepsis-induced acute lung injury by suppressing mitochondrial oxidative stress and PFKFB3-driven glycolysis

Abstract Background Sepsis is a potentially fatal condition with a significant risk of death. Acute lung injury (ALI) is a life-threatening complication of sepsis, and the inflammatory response plays a critical role in sepsis-induced ALI. The protective effects of micheliolide (MCL) against renal fi...

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Detalhes bibliográficos

Principais autores:	Wenhan Li, Yuhan Li, Linjie Xiao, Zhanzhan Xie, Jun Peng, Wenhui Huang, Xu Li, Ying Meng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-02-01
Colecção:	Journal of Translational Medicine
Assuntos:	Acute lung injury Macrophage polarization Oxidative stress PFKFB3 Glycolysis
Acesso em linha:	https://doi.org/10.1186/s12967-024-05906-0
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