Rad52 mediates class-switch DNA recombination to IgD
IgD is expressed, predominantly together with IgM, via mRNA alternative splicing, but IgD class switch recombination (IgD CSR) has also been reported. Here the authors show, using Rad52-deficient mouse and human B cells, that IgD CSR is mediated by Rad52 through an alternative, microhomology-based e...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Portfolio
2022-02-01
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| Colección: | Nature Communications |
| Acceso en línea: | https://doi.org/10.1038/s41467-022-28576-2 |
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