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Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86.

DNA ends are generated during double-strand-break repair and recombination. A p70-p86 heterodimer, Ku, accounts for the DNA end binding activity in eukaryotic cell extracts. When one or both subunits of Ku are missing, mammalian cells are deficient in double-strand-break repair and in specialized re...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Wu, X, Lieber, M R
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231519/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8756676/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.9.5186
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