Epigenetic regulation of TXNIP-mediated oxidative stress and NLRP3 inflammasome activation contributes to SAHH inhibition-aggravated diabetic nephropathy

S-adenosylhomocysteine (SAH) is hydrolyzed by SAH hydrolase (SAHH) to homocysteine and adenosine. Increased plasma SAH levels were associated with disturbed renal function in patients with diabetes. However, the role and mechanism of SAHH in diabetic nephropathy is still unknown. In the present stud...

Descrición completa

Detalles Bibliográficos

Principais autores:	Xin Dai, Ruyi Liao, Chaoqun Liu, Si Liu, Haiyan Huang, Jianjun Liu, Tianru Jin, Honghui Guo, Zhihua Zheng, Min Xia, Wenhua Ling, Yunjun Xiao
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2021-09-01
Series:	Redox Biology
Assuntos:	S-adenosylhomocysteine Diabetic nephropathy Thioredoxin-interacting protein Nod-like receptor protein 3 Early growth response 1
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2213231721001919
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!