BiGKbhb: a bi-directional gated recurrent unit model for predicting lysine β-hydroxybutyrylation sites

Abstract Post-Translational Modifications (PTMs) are covalent chemical alterations that occur after protein synthesis, critically regulating protein function, localization, and interactions. β-hydroxybutyrylation (Kbhb), a metabolically derived histone modification discovered in 2016, influences gen...

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Κύριοι συγγραφείς:	Heba M. Elreify, Fathi E. Abd El-Samie, Moawad I. Dessouky, Hanaa Torkey, Said E. El-Khamy, Wafaa A. Shalaby
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2026-01-01
Σειρά:	BMC Genomics
Θέματα:	Post-translational modifications Β-hydroxybutyrylation Kbhb BLOSUM Bidirectional gated recurrent unit Protein language models
Διαθέσιμο Online:	https://doi.org/10.1186/s12864-025-12166-9
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