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The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress

The conserved protein RIF1 stabilizes replication factories and regulates cohesin recruitment in response to replication stress to limit DNA lesions. Eukaryotic genomes are duplicated from thousands of replication origins that fire sequentially forming a defined spatiotemporal pattern of replication...

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Principais autores: Rana Lebdy, Julie Patouillard, Marion Larroque, Serge Urbach, Raghida Abou Merhi, Christian Larroque, Cyril Ribeyre
Formato: Artigo
Idioma:Inglês
Publicado: Life Science Alliance LLC 2023-04-01
Series:Life Science Alliance
Acceso en liña:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101186
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