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The organizer of chromatin topology RIF1 ensures cellular resilience to DNA replication stress

The conserved protein RIF1 stabilizes replication factories and regulates cohesin recruitment in response to replication stress to limit DNA lesions. Eukaryotic genomes are duplicated from thousands of replication origins that fire sequentially forming a defined spatiotemporal pattern of replication...

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主要な著者: Rana Lebdy, Julie Patouillard, Marion Larroque, Serge Urbach, Raghida Abou Merhi, Christian Larroque, Cyril Ribeyre
フォーマット: Artigo
言語:Inglês
出版事項: Life Science Alliance LLC 2023-04-01
シリーズ:Life Science Alliance
オンライン・アクセス:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202101186
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