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Tumor Hypoxia Regulates Immune Escape/Invasion: Influence on Angiogenesis and Potential Impact of Hypoxic Biomarkers on Cancer Therapies

The environmental and metabolic pressures in the tumor microenvironment (TME) play a key role in molding tumor development by impacting the stromal and immune cell fractions, TME composition and activation. Hypoxia triggers a cascade of events that promote tumor growth, enhance resistance to the ant...

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Detalhes bibliográficos
Principais autores: Raefa Abou Khouzam, Klaudia Brodaczewska, Aleksandra Filipiak, Nagwa Ahmed Zeinelabdin, Stephanie Buart, Cezary Szczylik, Claudine Kieda, Salem Chouaib
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-01-01
Colecção:Frontiers in Immunology
Assuntos:
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2020.613114/full
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