Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3

Spinocerebellar ataxia type 3 (SCA3) is an adult-onset, progressive ataxia. SCA3 presents with ataxia before any gross neuropathology. A feature of many cerebellar ataxias is aberrant cerebellar output that contributes to motor dysfunction. We examined whether abnormal cerebellar output was present...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Kristin Mayoral-Palarz, Andreia Neves-Carvalho, Sara Duarte-Silva, Daniela Monteiro-Fernandes, Patrícia Maciel, Kamran Khodakhah
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	The Company of Biologists 2022-08-01
Cyfres:	Disease Models & Mechanisms
Pynciau:	cerebellum ataxia sca3 purkinje cells
Mynediad Ar-lein:	http://dmm.biologists.org/content/15/8/dmm049514
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!