Effective analysis of testicular seminoma toxicity and mechanisms of acetyl tributyl citrate using network toxicology, bulk RNA sequencing data, single-cell RNA sequencing data, and clinical data

IntroductionAcetyl tributyl citrate (ATBC) is a widely used plasticizer ubiquitously present in the environment. Long-term high-dose ATBC exposure has been associated with reproductive system damage, yet its toxic effects and underlying mechanisms in testicular seminoma remain unclear. This study ai...

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Autori principali:	Haisheng Yi, Yibo Gong, Wenjie Yang, Yinzhao Jia, Jintao Chen, Chao Zhang, Xueming Lin, Hua Tian, Bo Wu, Xiaoming Cao, Gang Liang, Xiaobin Yuan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-07-01
Serie:	Frontiers in Immunology
Soggetti:	acetyl tributyl citrate prognostic genes risk model single-cell RNA sequencing testicular seminoma
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1752528/full
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