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Effective analysis of testicular seminoma toxicity and mechanisms of acetyl tributyl citrate using network toxicology, bulk RNA sequencing data, single-cell RNA sequencing data, and clinical data

IntroductionAcetyl tributyl citrate (ATBC) is a widely used plasticizer ubiquitously present in the environment. Long-term high-dose ATBC exposure has been associated with reproductive system damage, yet its toxic effects and underlying mechanisms in testicular seminoma remain unclear. This study ai...

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Principais autores: Haisheng Yi, Yibo Gong, Wenjie Yang, Yinzhao Jia, Jintao Chen, Chao Zhang, Xueming Lin, Hua Tian, Bo Wu, Xiaoming Cao, Gang Liang, Xiaobin Yuan
格式: Artigo
语言:Inglês
出版: Frontiers Media S.A. 2026-07-01
丛编:Frontiers in Immunology
主题:
acetyl tributyl citrate
prognostic genes
risk model
single-cell RNA sequencing
testicular seminoma
在线阅读:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1752528/full
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