Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences
Serine/arginine-rich splicing factor 2 (SRSF2) is a member of the SR protein family that is involved in both constitutive and alternative mRNA splicing. Mutations in SRSF2 gene are frequently reported in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). It is imperative to understand...
Salvato in:
| Autori principali: | , , , , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2019-04-01
|
| Serie: | Frontiers in Genetics |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/article/10.3389/fgene.2019.00338/full |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|