Lower in vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer’s pathology: a cohort study
Abstract Background Autopsy work indicates that the widely-projecting noradrenergic pontine locus coeruleus (LC) is among the earliest regions to accumulate hyperphosphorylated tau, a neuropathological Alzheimer’s disease (AD) hallmark. This early tau deposition is accompanied by a reduced density o...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BMC
2024-06-01
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| سلاسل: | Alzheimer’s Research & Therapy |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s13195-024-01500-0 |
| الوسوم: |
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