AIB1 sequestration by androgen receptor inhibits estrogen-dependent cyclin D1 expression in breast cancer cells

Abstract Background Androgens, through their own receptor, play a protective role on breast tumor development and progression and counterbalance estrogen-dependent growth stimuli which are intimately linked to breast carcinogenesis. Methods Cell counting by trypan blu exclusion was used to study and...

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Detalhes bibliográficos

Principais autores:	Francesca De Amicis, Chiara Chiodo, Catia Morelli, Ivan Casaburi, Stefania Marsico, Rosalinda Bruno, Diego Sisci, Sebastiano Andò, Marilena Lanzino
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-11-01
coleção:	BMC Cancer
Assuntos:	Breast cancer MCF-7 Androgen receptor Estrogen receptor Dihydrotestosterone Estradiol
Acesso em linha:	http://link.springer.com/article/10.1186/s12885-019-6262-4
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