scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing

Abstract Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently, a pipeline does not exist to maximize variant calling accuracy. Furthermore, molecular duplicates generated in these experiments have not been utilized to...

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Bibliografske podrobnosti

Principais autores:	Gavin W. Wilson, Mathieu Derouet, Gail E. Darling, Jonathan C. Yeung
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2021-05-01
Serija:	Genome Biology
Teme:	Single-cell RNA-seq Genetic variation Alignment Variant calling
Online dostop:	https://doi.org/10.1186/s13059-021-02364-5
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