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scSNV: accurate dscRNA-seq SNV co-expression analysis using duplicate tag collapsing

Abstract Identifying single nucleotide variants has become common practice for droplet-based single-cell RNA-seq experiments; however, presently, a pipeline does not exist to maximize variant calling accuracy. Furthermore, molecular duplicates generated in these experiments have not been utilized to...

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Hlavní autoři: Gavin W. Wilson, Mathieu Derouet, Gail E. Darling, Jonathan C. Yeung
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2021-05-01
Edice:Genome Biology
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On-line přístup:https://doi.org/10.1186/s13059-021-02364-5
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