ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency
<p>Abstract</p> <p>Background</p> <p>The herpes simplex virus type 1 (HSV-1) ICP0 protein is an E3 ubiquitin ligase, which is encoded within the HSV-1 latency-associated locus. When ICP0 is not synthesized, the HSV-1 genome is acutely susceptible to cellular repression. Reciprocally, when ICP0 is sy...
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| Автори: | , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2006-06-01
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| Серія: | Virology Journal |
| Онлайн доступ: | http://www.virologyj.com/content/3/1/44 |
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