Subcellular localization of PD‐L1 and cell‐cycle‐dependent expression of nuclear PD‐L1 variants: implications for head and neck cancer cell functions and therapeutic efficacy

The programmed cell death 1 ligand 1 (PD‐L1)/programmed cell death protein 1 (PD‐1) axis is primarily associated with immunosuppression in cytotoxic T lymphocytes (CTLs). However, mounting evidence is supporting the thesis that PD‐L1 not only functions as a ligand but mediates additional cellular fu...

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Ngā kaituhi matua:	Daniela Schulz, Laura Feulner, Dominique Santos Rubenich, Sina Heimer, Sophia Rohrmüller, Yvonne Reinders, Marcelo Falchetti, Martin Wetzel, Elizandra Braganhol, Edroaldo Lummertz da Rocha, Nicole Schäfer, Sabine Stöckl, Gero Brockhoff, Anja K. Wege, Jürgen Fritsch, Fabian Pohl, Torsten E. Reichert, Tobias Ettl, Richard J. Bauer
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Wiley 2024-02-01
Rangatū:	Molecular Oncology
Ngā marau:	DNA remodeling HNSCC nPD‐L1 nuclear trafficking subcellular protein fractionation vimentin immunotherapy
Urunga tuihono:	https://doi.org/10.1002/1878-0261.13567
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!