Breast cancer scoring based on a multiplexed profiling of soluble and cell-associated (immune) markers facilitates the prediction of pembrolizumab therapy

Abstract Background The immune checkpoint targeting is nowadays an integral part of cancer therapies. However, only a minority of patients experience long-term benefits. Thus, the identification of predictive biomarkers contributing to therapy response is urgently needed. Methods Here, we analyzed d...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Verena Schweihofer, Christina Bruss, Stephan Seitz, Gunther Glehr, Madeleine Hetterich, Florian Weber, Maria Hatzipanagiotou, Miriam Fernández-Pacheco Álvarez, Olaf Ortmann, Gero Brockhoff, Richard J. Bauer, Anja Kathrin Wege
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-03-01
coleção:	Cancer Cell International
Assuntos:	Checkpoint expression Checkpoint secretion Soluble factors Checkpoint therapy Breast cancer (BC) Tumor phenotype
Acesso em linha:	https://doi.org/10.1186/s12935-025-03729-7
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!