SAFE-MIL: a statistically interpretable framework for screening potential targeted therapy patients based on risk estimation

Patients with the target gene mutation frequently derive significant clinical benefits from target therapy. However, differences in the abundance level of mutations among patients resulted in varying survival benefits, even among patients with the same target gene mutations. Currently, there is a la...

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Detalhes bibliográficos

Principais autores:	Yanfang Guan, Zhengfa Xue, Jiayin Wang, Xinghao Ai, Rongrong Chen, Xin Yi, Shun Lu, Yuqian Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-08-01
coleção:	Frontiers in Genetics
Assuntos:	EGFR non-small cell lung cancer target therapy risk estimation Hosmer-Lemeshow test multi-instance learning
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fgene.2024.1381851/full
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