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Prohibitin 2 ameliorates cisplatin-induced acute kidney injury by modulating mitochondrial homeostasis

Acute kidney injury (AKI), associated with a major health burden globally, is frequently caused by nephrotoxic agents, specifically cisplatin. Prohibitin (PHB) 2, a highly conserved mitochondrial protein localized at the inner mitochondrial membrane, is key to maintaining mitochondrial respiration,...

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Principais autores: Qi Zhang, Xiaoyu Shi, Lu Yao, Ping Zhou, Wei Ding
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2025-12-01
Series:Frontiers in Physiology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fphys.2025.1658685/full
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