Ubiquitin-specific protease 13 promotes colorectal cancer progression by stabilizing mitogen-activated protein kinase kinase 3

Abstract The deubiquitinase ubiquitin-specific protease 13 (USP13) has been implicated in various cancers, yet its precise molecular function and clinical significance in colorectal cancer (CRC) remain poorly defined. Here, we identify USP13 as a critical regulator of CRC progression through systema...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Si-yu Chang, Bo Gu, Yong Xiong, Meng-si Zhao, Le Li, Yi Liu, Bai-qi Wang, Guo-qing Li, Run-lei Du, Xiao-dong Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-11-01
Edice:	Molecular Biomedicine
Témata:	Colorectal cancer USP13 MKK3 P38 MAPK signaling Deubiquitination Tumor progression
On-line přístup:	https://doi.org/10.1186/s43556-025-00375-3
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!