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Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and reg...

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Autori principali: Pankaj Deo, Seong H Chow, Iain D Hay, Oded Kleifeld, Adam Costin, Kirstin D Elgass, Jhih-Hang Jiang, Georg Ramm, Kipros Gabriel, Gordon Dougan, Trevor Lithgow, Eva Heinz, Thomas Naderer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2018-03-01
Serie:PLoS Pathogens
Accesso online:https://doi.org/10.1371/journal.ppat.1006945
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