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Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB is also targeted to host mitochondria and reg...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Pankaj Deo, Seong H Chow, Iain D Hay, Oded Kleifeld, Adam Costin, Kirstin D Elgass, Jhih-Hang Jiang, Georg Ramm, Kipros Gabriel, Gordon Dougan, Trevor Lithgow, Eva Heinz, Thomas Naderer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2018-03-01
Schriftenreihe:PLoS Pathogens
Online-Zugang:https://doi.org/10.1371/journal.ppat.1006945
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