Glucosylceramide synthesis and synthase expression protect against ceramide-induced stress

Ceramides (Cers), critical for epidermal barrier function, also can inhibit keratinocyte proliferation, while glucosylceramides (GlcCers) exert pro-mitogenic effects. Since alterations in Cer-to-GlcCer ratios appear to modulate cellular growth versus apoptosis, we assessed whether keratinocytes up-r...

Descripció completa

Dades bibliogràfiques

Autors principals:	Yoshikazu Uchida, Satoru Murata, Matthias Schmuth, Martin J. Behne, Jeong Deuk Lee, Shinichi Ichikawa, Peter M. Elias, Yoshio Hirabayashi, Walter M. Holleran
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2002-08-01
Col·lecció:	Journal of Lipid Research
Matèries:	keratinocytes apoptosis cutaneous sphingomyelin sphingolipids
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227520300614
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!