Strategies for Genetically Engineering Hypoimmunogenic Universal Pluripotent Stem Cells

Despite progress in developing cell therapies, such as T cell or stem cell therapies to treat diseases, immunoincompatibility remains a major barrier to clinical application. Given the fact that a host's immune system may reject allogeneic transplanted cells, methods have been developed to genetical...

Full description

Bibliographic Details

Main Authors:	Wei Zhao, Anhua Lei, Lin Tian, Xudong Wang, Cristina Correia, Taylor Weiskittel, Hu Li, Alan Trounson, Qiuli Fu, Ke Yao, Jin Zhang
Format:	Artigo
Language:	Inglês
Published:	Elsevier 2020-06-01
Series:	iScience
Subjects:	Biological Sciences Genetic Engineering Cell Biology Stem Cells Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004220303473
Tags:	Add Tag No Tags, Be the first to tag this record!